How to administer INVEGA TRINZA®


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  • INVEGA TRINZA® should be administered by a healthcare professional as a single injection
  • DO NOT divide dose into multiple injections
  • INVEGA TRINZA® is intended for intramuscular use only. Inject slowly, deep into the muscle, taking care to avoid injection into a blood vessel
  • Read complete instructions prior to use


This medication should be administered once every 3 months.


Peel off tab label from the syringe and place in patient record.

INVEGA TRINZA® requires longer and more vigorous shaking than INVEGA SUSTENNA® (1-month paliperidone palmitate extended-release injectable suspension). Shake the syringe vigorously, with the syringe tip pointing up, for at least 15 seconds within 5 minutes prior to administration (see Step 2).

INVEGA TRINZA<sup>®</sup> requires long and vigorous shaking, at least 15 seconds within 5 minutes prior to administration

Thin Wall Safety Needle Selection1

Thin wall safety needles are designed to be used with INVEGA TRINZA®. Therefore, it is important to only use the needles provided in the INVEGA TRINZA® kit.


    Diagram of Dose pack contents Diagram of needle selection How to prepare for an injection Steps after preparing for an injection Inject dose and dispose of needle

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Reference: 1. INVEGA TRINZA® [prescribing information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; March 2016.