Instructions for Preparing an INVEGA TRINZA® Injection1
With the syringe tip pointing up, SHAKE VIGOROUSLY with a loose wrist for at least 15 seconds to ensure a homogeneous suspension.
NOTE: This medication requires longer and more vigorous shaking than the 1-month paliperidone palmitate extended-release injectable suspension.
After shaking the syringe for at least 15 seconds, check the liquid in the viewing window. The suspension should appear uniform and milky white in color. It is also normal to see small air bubbles.
First, open needle pouch by peeling the cover back halfway. Place on a clean surface.
Then, holding the syringe upright, twist and pull the rubber cap to remove.
Fold back needle cover and plastic tray. Then, firmly grasp the needle sheath through the pouch, as shown.
With your other hand, hold the syringe by the Luer connection and attach it to the safety needle with a gentle clockwise twisting motion.
Do not remove the pouch until the syringe and needle are securely attached.
Pull the needle sheath away from the needle in a straight motion.
Do not twist the sheath, as this may loosen the needle from the syringe.
Hold the syringe upright and tap gently to make any air bubbles rise to the top.
Remove air by pressing the plunger rod upward carefully until a drop of liquid comes out of the needle tip.
INVEGA TRINZA® Injection1
Slowly inject the entire contents of the syringe intramuscularly, deep into the selected deltoid or gluteal muscle.
Do not administer by any other route.
After INVEGA TRINZA® Injection1
After the injection is complete, use your thumb or a flat surface to secure the needle in the safety device.
The needle is secure when a “click” sound is heard.
Dispose of the syringe and unused needle in an approved Sharps Container.
IMPORTANT: Thin wall safety needles are designed specifically for use with INVEGA TRINZA®. Unused needle should be discarded and not saved for future use.
Reference: 1. INVEGA TRINZA® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; August 2021.