Extrapyramidal Symptoms Data Observed1

Extrapyramidal symptoms (EPS) data: 
Long-term maintenance trial1 
EPS-related reactions by MedDRA-preferred term1
A chart that illustrates the extrapyramidal symptoms (EPS) observed in patients taking INVEGA TRINZA® in a clinical study

MedDRA=Medical Dictionary for Regulatory Activities.

*During the open-label phase, patients received several doses of INVEGA SUSTENNA® (paliperidone palmitate) followed by a single dose of INVEGA TRINZA®.

Parkinsonism group included: cogwheel rigidity, drooling, extrapyramidal disorder, hypokinesia, muscle rigidity, muscle tightness, musculoskeletal stiffness, parkinsonism.

Hyperkinesia group included: akathisia, restlessness.

§Dystonia group included: blepharospasm, dystonia, muscle spasms.

Reference: 1. INVEGA TRINZA® [prescribing information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; February 2017.