Extrapyramidal Symptoms Data Observed1
Long-term maintenance trial1
EPS-related reactions by MedDRA-preferred term1
MedDRA=Medical Dictionary for Regulatory Activities.
*During the open-label phase, patients received several doses of INVEGA SUSTENNA® (paliperidone palmitate) followed by a single dose of INVEGA TRINZA®.
†Parkinsonism group included: cogwheel rigidity, drooling, extrapyramidal disorder, hypokinesia, muscle rigidity, muscle tightness, musculoskeletal stiffness, parkinsonism.
‡Hyperkinesia group included: akathisia, restlessness.
§Dystonia group included: blepharospasm, dystonia, muscle spasms.
Reference: 1. INVEGA TRINZA® [prescribing information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; February 2017.