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INVEGA TRINZA® Injection Video | HCP

Preparing for Injection1


Inadequate preparation could result in a clogged needle and potential incomplete administration of dose.1

  • With the tip pointing up, shake syringe vigorously with a loose wrist for at least 15 seconds. Administer within 5 minutes of shaking.1
  • When the mixture is appropriately homogenized, the suspension should appear uniform and milky white in color. It is also normal to see small air bubbles. Remember—the suspension can not be overmixed.1
  • Whether administering in deltoid or gluteal muscle, you should alternate injections between each muscle. For instance, if you inject in deltoid, alternate between left and right deltoid.1

For intramuscular injection only. Do not administer by any other route.1


Important Administration Information


  • INVEGA TRINZA® should be administered by a healthcare professional as a single injection. DO NOT divide dose into multiple injections
  • INVEGA TRINZA® is intended for intramuscular use only. Inject slowly, deep into the muscle, taking care to avoid injection into a blood vessel
  • Read complete instructions prior to use


This medication should be administered once every 3 months.

Thin wall safety needle selection1

  • Thin wall safety needles are designed to be used with INVEGA TRINZA®. Therefore, it is important to only use the needles provided in the INVEGA TRINZA® kit


  • Peel off tab label from the syringe and place in patient record
  • INVEGA TRINZA® requires longer and more vigorous shaking than INVEGA SUSTENNA® (1-month paliperidone palmitate extended-release injectable suspension). Shake the syringe vigorously with a loose wrist, with the syringe tip pointing up, for at least 15 seconds within 5 minutes prior to administration
Reference: 1. INVEGA TRINZA® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; August 2021.